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Population pharmacokinetic and pharmacodynamic properties of artesunate in patients with artemisinin sensitive and resistant infections in Southern Myanmar

BACKGROUND: Artemisinins are the most effective anti-malarial drugs for uncomplicated and severe Plasmodium falciparum malaria. However, widespread artemisinin resistance in the Greater Mekong Region of Southeast Asia is threatening the possibility to control and eliminate malaria. This work aimed t...

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Detalles Bibliográficos
Autores principales: Lohy Das, Jesmin Permala, Kyaw, Myat P., Nyunt, Myat H., Chit, Khin, Aye, Kyin H., Aye, Moe M., Karlsson, Mats O., Bergstrand, Martin, Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865368/
https://www.ncbi.nlm.nih.gov/pubmed/29566683
http://dx.doi.org/10.1186/s12936-018-2278-5