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Dexmedetomidine attenuates lung apoptosis induced by renal ischemia–reperfusion injury through α(2)AR/PI3K/Akt pathway
BACKGROUND: Acute lung injury caused by renal ischemia–reperfusion is one of the leading causes of acute kidney injury-related death. Dexmedetomidine, an α(2)-adrenergic agonist sedative, has been found to have protective effects against acute kidney injury and remote lung injury. We sought to deter...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865375/ https://www.ncbi.nlm.nih.gov/pubmed/29566706 http://dx.doi.org/10.1186/s12967-018-1455-1 |