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Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal models and are unrepresented in leukemia cell lines....

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Detalles Bibliográficos
Autores principales:	Sinclair, Paul. B., Blair, Helen H., Ryan, Sarra L., Buechler, Lars, Cheng, Joanna, Clayton, Jake, Hanna, Rebecca, Hollern, Shaun, Hawking, Zoe, Bashton, Matthew, Schwab, Claire J., Jones, Lisa, Russell, Lisa J., Marr, Helen, Carey, Peter, Halsey, Christina, Heidenreich, Olaf, Moorman, Anthony V., Harrison, Christine J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865429/ https://www.ncbi.nlm.nih.gov/pubmed/29449437 http://dx.doi.org/10.3324/haematol.2017.172304

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