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Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome

Differentiation of hematopoietic stem cells is regulated by a concert of different transcription factors. Disturbed transcription factor function can be the basis of (pre)malignancies such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Growth factor independence 1b (Gfi1b) is a r...

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Detalles Bibliográficos
Autores principales: Thivakaran, Aniththa, Botezatu, Lacramioara, Hönes, Judith M., Schütte, Judith, Vassen, Lothar, Al-Matary, Yahya S., Patnana, Pradeep, Zeller, Amos, Heuser, Michael, Thol, Felicitas, Gabdoulline, Razif, Olberding, Nadine, Frank, Daria, Suslo, Marina, Köster, Renata, Lennartz, Klaus, Görgens, Andre, Giebel, Bernd, Opalka, Bertram, Dührsen, Ulrich, Khandanpour, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865438/
https://www.ncbi.nlm.nih.gov/pubmed/29326122
http://dx.doi.org/10.3324/haematol.2017.167288