A Method for Characterising Human Intervertebral Disc Glycosaminoglycan Disaccharides using Liquid Chromatography-Mass Spectrometry with Multiple Reaction Monitoring

Intervertebral disc (IVD) degeneration results in the depletion of proteoglycans and glycosaminoglycans (GAGs), which can lead to structural and mechanical loss of IVD function, ingrowth of nociceptive nerve fbres and eventually discogenic pain. Specifc GAG types as well as their disaccharide patern...

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Detalles Bibliográficos
Autores principales: Liu, X., Krishnamoorthy, D., Lin, L., Xue, P., Zhang, F., Chi, L., Linhardt, R.J., Iatridis, J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865475/
https://www.ncbi.nlm.nih.gov/pubmed/29469163
http://dx.doi.org/10.22203/eCM.v035a09

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865475/
https://www.ncbi.nlm.nih.gov/pubmed/29469163
http://dx.doi.org/10.22203/eCM.v035a09

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