The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells

Free fatty acids (FFAs) can cause glucose intolerance and diabetes. Lipotoxicity to the pancreatic beta cells is considered to be a major underlying cause for this phenomenon. The aim of this study was to analyse the toxicity profile of FFAs in the human EndoC-βH1 beta-cell line and to compare the r...

Descripción completa

Detalles Bibliográficos
Autores principales: Plötz, T, Krümmel, B, Laporte, A, Pingitore, A, Persaud, SJ, Jörns, A, Elsner, M, Mehmeti, I, Lenzen, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865546/
https://www.ncbi.nlm.nih.gov/pubmed/29269872
http://dx.doi.org/10.1038/s41387-017-0005-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865546/
https://www.ncbi.nlm.nih.gov/pubmed/29269872
http://dx.doi.org/10.1038/s41387-017-0005-x

Ejemplares similares