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Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells

The study of eukaryotic initiation factor 4E (eIF4E) is a key focus in cancer research due to its role in controlling the translation of tumour-associated proteins, that drive an aggressive migratory phenotype. eIF4E is a limiting component of the eIF4F complex which is a critical determinant for th...

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Detalles Bibliográficos
Autores principales:	Lineham, Ella, Tizzard, Graham J., Coles, Simon J., Spencer, John, Morley, Simon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865660/ https://www.ncbi.nlm.nih.gov/pubmed/29581834 http://dx.doi.org/10.18632/oncotarget.24354

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