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Cell internalization of 7-ketocholesterol-containing nanoemulsion through LDL receptor reduces melanoma growth in vitro and in vivo: a preliminary report

Oxysterols are cholesterol oxygenated derivatives which possess several biological actions. Among oxysterols, 7-ketocholesterol (7KC) is known to induce cell death. Here, we hypothesized that 7KC cytotoxicity could be applied in cancer therapeutics. 7KC was incorporated into a lipid core nanoemulsio...

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Detalles Bibliográficos
Autores principales:	Favero, Giovani M., Paz, Jessica L., Otake, Andréia H., Maria, Durvanei A., Caldini, Elia G., de Medeiros, Raphael S.S., Deus, Debora F., Chammas, Roger, Maranhão, Raul C., Bydlowski, Sergio P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865661/ https://www.ncbi.nlm.nih.gov/pubmed/29581835 http://dx.doi.org/10.18632/oncotarget.24389

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