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Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer
Fibulin 5 (FBLN5) is an extracellular matrix glycoprotein that suppresses matrix metalloprotease 9 (MMP-9), angiogenesis and epithelial cell motility. Here, we investigated the regulation and function of FBLN5 in epithelial ovarian cancer (EOC). FBLN5 mRNA was down-regulated 5-fold in EOC relative t...
Autores principales: | Manders, Dustin B., Kishore, Hari Annavarapu, Gazdar, Adi F., Keller, Patrick W., Tsunezumi, Jun, Yanagisawa, Hiromi, Lea, Jayanthi, Word, Ruth Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865667/ https://www.ncbi.nlm.nih.gov/pubmed/29581841 http://dx.doi.org/10.18632/oncotarget.24484 |
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