Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer

While several molecular targets have been identified for adenocarcinoma (ACA) of the lung, similar drivers with squamous cell carcinoma (SCC) are sparse. We compared signaling pathways and potential therapeutic targets in lung SCC and ACA tumors using reverse phase proteomic arrays (RPPA) from two i...

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Detalles Bibliográficos
Autores principales: Gomez, Daniel Richard, Byers, Lauren Averett, Nilsson, Monique, Diao, Lixia, Wang, Jing, Li, Lerong, Tong, Pan, Hofstad, Mia, Saigal, Babita, Wistuba, Ignacio, Kalhor, Neda, Swisher, Stephen, Fan, Youhong, Hong, Waun Ki, Suraokar, Milind, Behrens, Carmen, Moran, Cesar, Heymach, John Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865668/
https://www.ncbi.nlm.nih.gov/pubmed/29581842
http://dx.doi.org/10.18632/oncotarget.24361

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