Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells

Systemic anaplastic large-cell lymphoma (ALCL) is a childhood T cell neoplasm defined by the presence or absence of translocations that lead to the ectopic expression of anaplastic lymphoma kinase (ALK), with nucleophosmin-ALK (NPM-ALK) fusions being the most common. Polychemotherapy involving doxor...

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Detalles Bibliográficos
Autores principales: Congras, Annabelle, Caillet, Nina, Torossian, Nouritza, Quelen, Cathy, Daugrois, Camille, Brousset, Pierre, Lamant, Laurence, Meggetto, Fabienne, Hoareau-Aveilla, Coralie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865688/
https://www.ncbi.nlm.nih.gov/pubmed/29581862
http://dx.doi.org/10.18632/oncotarget.24465

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