Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity

Methylation at the 5 position of cytosine in DNA (5meC), is a key epigenetic mark in eukaryotes. Once introduced, 5meC can be maintained through DNA replication due to the activity of “maintenance” DNA methyltransferases.. Despite their ancient origin, DNA methylation pathways differ widely across m...

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Detalles Bibliográficos
Autores principales: Rošić, Silvana, Amouroux, Rachel, Requena, Cristina E., Gomes, Ana, Emperle, Max, Beltran, Toni, Rane, Jayant K., Linnett, Sarah, Selkirk, Murray E., Schiffer, Philipp H., Bancroft, Allison J., Grencis, Richard K., Jeltsch, Albert, Hajkova, Petra, Sarkies, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865749/
https://www.ncbi.nlm.nih.gov/pubmed/29459678
http://dx.doi.org/10.1038/s41588-018-0061-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865749/
https://www.ncbi.nlm.nih.gov/pubmed/29459678
http://dx.doi.org/10.1038/s41588-018-0061-8

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