Cargando…
Periostin cross-reacts with the renin-angiotensin system during liver fibrosis development
Periostin is a 90-kDa extracellular matrix protein, which is secreted primarily from fibroblasts and is expressed in the lungs, kidneys and heart valves. Angiotensin II (AT-II) serves pivotal roles in the pathogenesis of several diseases with accompanying fibrosis, including chronic liver diseases....
Autores principales: | Takeda, Kosuke, Noguchi, Ryuichi, Kitade, Mitsuteru, Namisaki, Tadashi, Moriya, Kei, Kawaratani, Hideto, Okura, Yasushi, Kaji, Kosuke, Aihara, Yosuke, Douhara, Akitoshi, Nishimura, Norihisa, Sawada, Yasuhiko, Seki, Kenichiro, Yoshiji, Hitoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865756/ https://www.ncbi.nlm.nih.gov/pubmed/28849131 http://dx.doi.org/10.3892/mmr.2017.7356 |
Ejemplares similares
-
Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model
por: DOUHARA, AKITOSHI, et al.
Publicado: (2015) -
DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis
por: Asada, Kiyoshi, et al.
Publicado: (2016) -
Novel oral plasminogen activator inhibitor-1 inhibitor TM5275 attenuates hepatic fibrosis under metabolic syndrome via suppression of activated hepatic stellate cells in rats
por: Noguchi, Ryuichi, et al.
Publicado: (2020) -
Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats
por: Nishimura, Norihisa, et al.
Publicado: (2018) -
Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model
por: Seki, Kenichiro, et al.
Publicado: (2018)