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Anti-angiogenesis gene therapy for hepatocellular carcinoma via systemic injection of mesenchymal stem cells engineered to secrete soluble Flt-1

Anti-angiogenesis gene therapy has attracted interest as a potential treatment for hepatocellular carcinoma (HCC). Studies have indicated that soluble fms-like tyrosine kinase-1 (sFlt-1) may suppress angiogenesis by sequestering free vascular endothelial growth factor (VEGF) or by forming inactive h...

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Detalles Bibliográficos
Autores principales:	Li, Guanglin, Miao, Fei, Zhu, Jinhai, Chen, Yanling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865760/ https://www.ncbi.nlm.nih.gov/pubmed/28849176 http://dx.doi.org/10.3892/mmr.2017.7310

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