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Tumor necrosis factor-α and interleukin-6 suppress microRNA-1275 transcription in human adipocytes through nuclear factor-κB

Obesity is a confirmed risk factor for hyperlipidemia, type-II diabetes, hypertension, and cardiovascular disease. MicroRNAs (miRs) have emerged as an important field of study within energy metabolism and obesity. A previous study demonstrated miR-1275 to be markedly down-regulated during maturation...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-Feng, Fu, Zi-Yi, Chen, Xiao-Hui, Cui, Yan, Ji, Chen-Bo, Guo, Xi-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865775/
https://www.ncbi.nlm.nih.gov/pubmed/28901460
http://dx.doi.org/10.3892/mmr.2017.7392