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High glucose and high insulin conditions promote MCF-7 cell proliferation and invasion by upregulating IRS1 and activating the Ras/Raf/ERK pathway

Diabetes mellitus is associated with an increased risk of breast cancer, but the molecular mechanism underlying this association remains unclear. The aim of the present study was to investigate the effect of high glucose and high insulin conditions on MCF-7 breast cancer cells and to elucidate the m...

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Detalles Bibliográficos
Autores principales:	Wei, Mei-Lin, Duan, Peng, Wang, Zhi-Ming, Ding, Miao, Tu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865785/ https://www.ncbi.nlm.nih.gov/pubmed/28901503 http://dx.doi.org/10.3892/mmr.2017.7420

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