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N-acetylcysteine induces apoptosis via the mitochondria-dependent pathway but not via endoplasmic reticulum stress in H9c2 cells

N-acetylcysteine (NAC), a precursor of glutathione, is a widely used thiol-containing antioxidant and modulator of the intracellular redox state. Our previous study demonstrated that excess reduced glutathione (GSH) from NAC treatment paradoxically led to a reduction in glutathione redox potential,...

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Detalles Bibliográficos
Autores principales: Liu, Yuyong, Liu, Ke, Wang, Nian, Zhang, Huali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865795/
https://www.ncbi.nlm.nih.gov/pubmed/28901511
http://dx.doi.org/10.3892/mmr.2017.7442

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