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N-acetylcysteine induces apoptosis via the mitochondria-dependent pathway but not via endoplasmic reticulum stress in H9c2 cells
N-acetylcysteine (NAC), a precursor of glutathione, is a widely used thiol-containing antioxidant and modulator of the intracellular redox state. Our previous study demonstrated that excess reduced glutathione (GSH) from NAC treatment paradoxically led to a reduction in glutathione redox potential,...
Autores principales: | Liu, Yuyong, Liu, Ke, Wang, Nian, Zhang, Huali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865795/ https://www.ncbi.nlm.nih.gov/pubmed/28901511 http://dx.doi.org/10.3892/mmr.2017.7442 |
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