Cargando…

Protein kinase Cα stimulates hypoxia-induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal-regulated kinase 1/2 pathway

Hypoxic pulmonary hypertension (HPH) may contribute to vascular remodeling, and pulmonary artery smooth muscle cell (PASMC) proliferation has an important role in this process. However, no relevant information concerning the role and mechanism of protein kinase C (PKC)α in hypoxia-induced rat PASMC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Rui, Shi, Yiwei, Zeng, Chao, Yu, Wenyan, Zhang, Aizhen, Du, Yongcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865839/ https://www.ncbi.nlm.nih.gov/pubmed/28901444 http://dx.doi.org/10.3892/mmr.2017.7478

Ejemplares similares

Role of Rho kinase and Na(+)/H(+) exchange in hypoxia‐induced pulmonary arterial smooth muscle cell proliferation and migration
por: Walker, Jasmine, et al.
Publicado: (2016)

Protein kinase C isozyme expression in right ventricular hypertrophy induced by pulmonary hypertension in chronically hypoxic rats
por: Zeng, Chao, et al.
Publicado: (2017)

Resveratrol inhibits hypoxia-induced proliferation and migration of pulmonary artery vascular smooth muscle cells by inhibiting the phosphoinositide 3-kinase/protein kinase B signaling pathway
por: Guan, Zhanjiang, et al.
Publicado: (2017)

Inhibition of LIM kinase reduces contraction and proliferation in bladder smooth muscle
por: Yu, Qingfeng, et al.
Publicado: (2021)

Rosuvastatin inhibits the smooth muscle cell proliferation by targeting TNFα mediated Rho kinase pathway
por: Sun, Xiao, et al.
Publicado: (2012)

Glycogen Synthase Kinase 3beta Contributes to Proliferation of Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Sklepkiewicz, Piotr, et al.
Publicado: (2011)

Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation
por: Hernandez-Lara, Miguel A., et al.
Publicado: (2023)

Hypoxia Promotes Vascular Smooth Muscle Cell Proliferation through microRNA-Mediated Suppression of Cyclin-Dependent Kinase Inhibitors
por: Lee, Jihui, et al.
Publicado: (2019)

Hypoxia modulates the expression of leucine zipper-positive MYPT1 and its interaction with protein kinase G and Rho kinases in pulmonary arterial smooth muscle cells
por: Singh, Dev K., et al.
Publicado: (2011)

SENP-1 enhances hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia-inducible factor-1α
por: ZHOU, FANG, et al.
Publicado: (2016)

Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in‐vitro and pulmonary hypertension in mice
por: Chen, Tianji, et al.
Publicado: (2022)

Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling
por: Chen, Jiwang, et al.
Publicado: (2022)

Chemerin Stimulates Vascular Smooth Muscle Cell Proliferation and Carotid Neointimal Hyperplasia by Activating Mitogen-Activated Protein Kinase Signaling
por: Xiong, Wei, et al.
Publicado: (2016)

Sulfur Dioxide Inhibits Extracellular Signal-regulated Kinase Signaling to Attenuate Vascular Smooth Muscle Cell Proliferation in Angiotensin II-induced Hypertensive Mice
por: Wu, Hui-Juan, et al.
Publicado: (2016)

Rho kinase and Na(+)/H(+) exchanger mediate endothelin‐1‐induced pulmonary arterial smooth muscle cell proliferation and migration
por: Huetsch, John C., et al.
Publicado: (2018)

Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells
por: Chen, I-Shan, et al.
Publicado: (2011)

1α,25-Dihydroxyvitamin D(3) prevents the differentiation of human lung fibroblasts via microRNA-27b targeting the vitamin D receptor
por: LI, FEI, et al.
Publicado: (2015)

TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases
por: Chen, Gang, et al.
Publicado: (2006)

A spleen tyrosine kinase inhibitor attenuates the proliferation and migration of vascular smooth muscle cells
por: Seo, Hyang-Hee, et al.
Publicado: (2017)

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma
por: Hernandez-Lara, Miguel Angel, et al.
Publicado: (2022)

Inhibitory effect of Bailing capsule on hypoxia-induced proliferation of rat pulmonary arterial smooth muscle cells
por: Li, Xiaohui, et al.
Publicado: (2016)

NOD2 deficiency exacerbates hypoxia-induced pulmonary hypertension and enhances pulmonary vascular smooth muscle cell proliferation
por: Kwon, Min-Young, et al.
Publicado: (2018)

Myotubularin‐Related Protein14 Prevents Neointima Formation and Vascular Smooth Muscle Cell Proliferation by Inhibiting Polo‐Like Kinase1
por: Kong, Ling‐Yao, et al.
Publicado: (2022)

Oxidative Stress, Kinase Activation, and Inflammatory Pathways Involved in Effects on Smooth Muscle Cells During Pulmonary Artery Hypertension Under Hypobaric Hypoxia Exposure
por: Siques, Patricia, et al.
Publicado: (2021)

Adenylate Kinase 4—A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways
por: Wujak, Magdalena, et al.
Publicado: (2021)

Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
por: Xu, Dunquan, et al.
Publicado: (2013)

hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells
por: Li, Shan-Shan, et al.
Publicado: (2022)

Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression
por: Lee, Jihui, et al.
Publicado: (2023)

Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-Ping, et al.
Publicado: (2021)

Baicalin Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via the AKT/HIF-1α/p27-Associated Pathway
por: Zhang, Lin, et al.
Publicado: (2014)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells
por: Sang, Hai-yan, et al.
Publicado: (2016)

Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells
por: Deng, Jing-Ti, et al.
Publicado: (2019)

Diacylglycerol Kinase Puts the Brakes on Airway Smooth Muscle Contraction
por: Lukovic, Elvedin, et al.
Publicado: (2021)

Pharmacologic IRE1α kinase inhibition alleviates aortic dissection by decreasing vascular smooth muscle cells apoptosis
por: Zhang, Wenjun, et al.
Publicado: (2022)

Mechanism of Hypoxia-Mediated Smooth Muscle Cell Proliferation Leading to Vascular Remodeling
por: Huang, Xiaojuan, et al.
Publicado: (2022)

Hypoxia promotes cell proliferation by modulating E2F1 in chicken pulmonary arterial smooth muscle cells
por: Yang, Ying, et al.
Publicado: (2013)

MicroRNA-137 Inhibited Hypoxia-Induced Proliferation of Pulmonary Artery Smooth Muscle Cells by Targeting Calpain-2
por: Ge, Xiao-Yue, et al.
Publicado: (2021)

Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation
por: Ma, Cui, et al.
Publicado: (2022)

Cigarette Smoke Extract Stimulates Rat Pulmonary Artery Smooth Muscle Cell Proliferation via PKC-PDGFB Signaling
por: Xing, Ai-ping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jvmt8vg2ue3htlvca74n6h2ncj