Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro

Lysyl oxidase (LOX) is an enzyme that oxidizes lysine residues in collagens and elastin. It stabilizes or remodels the extracellular matrix and basement membrane of blood vessels. Current oncology studies have revealed that LOX is upregulated in invasive cancer cells and bolstered cell movement, and...

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Detalles Bibliográficos
Autores principales: Shi, Lin, Zhang, Ning, Liu, Hetao, Zhao, Lei, Liu, Jing, Wan, Juan, Wu, Wenyi, Lei, Hetian, Liu, Rongqing, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865964/
https://www.ncbi.nlm.nih.gov/pubmed/29393489
http://dx.doi.org/10.3892/mmr.2018.8508

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