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Evaluation of type 2 diabetic mellitus animal models via interactions between insulin and mitogen-activated protein kinase signaling pathways induced by a high fat and sugar diet and streptozotocin

Type 2 diabetic mellitus (T2DM), which is characterized by insulin resistance (IR), hyperglycemia and hyperlipidemia, is a comprehensive dysfunction of metabolism. The insulin receptor (INSR)/phosphoinositide 3-kinase (PI3K)/AKT signaling pathway is well acknowledged as a predominant pathway associa...

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Detalles Bibliográficos
Autores principales:	Zhuo, Juncheng, Zeng, Qiaohuang, Cai, Dake, Zeng, Xiaohui, Chen, Yuxing, Gan, Haining, Huang, Xuejun, Yao, Nan, Huang, Dane, Zhang, Chengzhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865978/ https://www.ncbi.nlm.nih.gov/pubmed/29393432 http://dx.doi.org/10.3892/mmr.2018.8504

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