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Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let-7c targeting of antiapoptotic BCL2L1

Colorectal cancer (CRC) remains a primary contributor to cancer-associated mortality. The Lin28/let-7 axis has previously been verified to participate in numerous pathophysiological processes involved in CRC. However, the potential roles and underlying mechanisms of this axis in apoptosis during CRC...

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Detalles Bibliográficos
Autores principales: Zhang, Haogang, Zong, Yaguang, Qiu, Gongcai, Jia, Ruichun, Xu, Xunzheng, Wang, Fujing, Wu, Dequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865979/
https://www.ncbi.nlm.nih.gov/pubmed/29393430
http://dx.doi.org/10.3892/mmr.2018.8483