Ouabain suppresses the growth and migration abilities of glioma U-87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF-1α

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Glioma is one of the most malignant forms of brain tumor, and has been of persistent concern due to its high recurrence and mortality rates, and limited therapeutic options. As a cardiac glycoside, ouabain has widespread applications in congestive heart diseases due to its positive cardiac inotropic...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-Sa, Xu, Zhong-Wei, Yi, Tai-Long, Xu, Rui-Cheng, Li, Jie, Zhang, Wen-Bin, Zhang, Sai, Sun, Hong-Tao, Yu, Ze-Qi, Xu, Hao-Xiang, Tu, Yue, Cheng, Shi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865999/
https://www.ncbi.nlm.nih.gov/pubmed/29436645
http://dx.doi.org/10.3892/mmr.2018.8587
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