Cargando…

Evolution of Sequence-Defined Highly Functionalized Nucleic Acid Polymers

The evolution of sequence-defined synthetic polymers made of building blocks beyond those compatible with polymerase enzymes or the ribosome has the potential to generate new classes of receptors, catalysts, and materials. Here we describe a ligase-mediated DNA-templated polymerization system and in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zhen, Lichtor, Phillip A., Berliner, Adrian P., Chen, Jonathan C., Liu, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866196/ https://www.ncbi.nlm.nih.gov/pubmed/29507367 http://dx.doi.org/10.1038/s41557-018-0008-9

Ejemplares similares

Enzyme-Free Translation of DNA into Sequence-Defined Synthetic Polymers Structurally Unrelated to Nucleic Acids
por: Niu, Jia, et al.
Publicado: (2013)

Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning
por: Chen, Jonathan C., et al.
Publicado: (2022)

Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation
por: Lichtor, Phillip A., et al.
Publicado: (2012)

Side-chain determinants of biopolymer function during selection and replication
por: Lichtor, Phillip A., et al.
Publicado: (2019)

Cationic Polymers as Transfection Reagents for Nucleic Acid Delivery
por: Cai, Xiaomeng, et al.
Publicado: (2023)

Evolution of an Enzyme from a Noncatalytic Nucleic Acid Sequence
por: Gysbers, Rachel, et al.
Publicado: (2015)

Molecular Evolution of Functional Nucleic Acids with Chemical Modifications
por: Kuwahara, Masayasu, et al.
Publicado: (2010)

DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers
por: Hili, Ryan, et al.
Publicado: (2012)

Experimental Lineage and Functional Analysis of a Remotely Directed Peptide Epoxidation Catalyst
por: Lichtor, Phillip A., et al.
Publicado: (2014)

End-joining long nucleic acid polymers
por: van den Hout, M., et al.
Publicado: (2008)

A High-Performance Polymer Composite Column for Coronavirus Nucleic Acid Purification
por: Zarouri, Akli, et al.
Publicado: (2023)

EasyDIVER: A Pipeline for Assembling and Counting High-Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Peptides
por: Blanco, Celia, et al.
Publicado: (2020)

Targeted high-throughput sequencing of tagged nucleic acid samples
por: Meyer, Matthias, et al.
Publicado: (2007)

Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages
por: Cozens, Christopher, et al.
Publicado: (2015)

The Inhibition of Anti-DNA Binding to DNA by Nucleic Acid Binding Polymers
por: Stearns, Nancy A., et al.
Publicado: (2012)

Helix control in polymers: Case of peptide nucleic acids (PNAs)
por: Totsingan, Filbert, et al.
Publicado: (2012)

Sequencing Ultrarare Targets with Compound Nucleic Acid Cytometry
por: Sun, Chen, et al.
Publicado: (2021)

FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins
por: Sukhanova, Maria V., et al.
Publicado: (2022)

Molecular Beacons of Xeno-Nucleic Acid for Detecting Nucleic Acid
por: Wang, Qi, et al.
Publicado: (2013)

Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy
por: Roehl, Ingo, et al.
Publicado: (2017)

Intracellular mRNA Regulation with Self-Assembled Locked Nucleic Acid Polymer Nanoparticles
por: Rush, Anthony M., et al.
Publicado: (2014)

New Applications of Lipid and Polymer-Based Nanoparticles for Nucleic Acids Delivery
por: Niculescu, Adelina-Gabriela, et al.
Publicado: (2021)

Nanoarchitectonics of Spherical Nucleic Acids with Biodegradable Polymer Cores: Synthesis and Evaluation
por: Kalinova, Radostina, et al.
Publicado: (2022)

Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics
por: Stoddard, Barry L, et al.
Publicado: (2018)

Impact of Nucleic Acid Sequencing on Viroid Biology
por: Adkar-Purushothama, Charith Raj, et al.
Publicado: (2020)

Metrological Support of Nucleic Acid Sequence Analysis
por: Melkova, O. N., et al.
Publicado: (2023)

Semiautomated synthesis of sequence-defined polymers for information storage
por: Lee, Jeong Min, et al.
Publicado: (2022)

Sequence- and structural-selective nucleic acid binding revealed by the melting of mixtures
por: Shi, Xiaochun, et al.
Publicado: (2006)

Functional nucleic acids as potent therapeutics against SARS-CoV-2 infection
por: Chen, Jingran, et al.
Publicado: (2023)

Selenium Derivatization of Nucleic Acids for Phase and Structure Determination in Nucleic Acid X-ray Crystallography
por: Sheng, Jia, et al.
Publicado: (2008)

Multiple sequence alignments of partially coding nucleic acid sequences
por: Stocsits, Roman R, et al.
Publicado: (2005)

Defining the Structure of a Protein–Spherical Nucleic Acid Conjugate and Its Counterionic Cloud
por: Krishnamoorthy, Kurinji, et al.
Publicado: (2018)

Defining the Design Parameters for in Vivo Enzyme Delivery Through Protein Spherical Nucleic Acids
por: Kusmierz, Caroline D., et al.
Publicado: (2020)

Modified nucleic acids: replication, evolution, and next-generation therapeutics
por: Duffy, Karen, et al.
Publicado: (2020)

CRISPR/Cas systems for the detection of nucleic acid and non-nucleic acid targets
por: Su, Weiran, et al.
Publicado: (2023)

Identification of nucleic acid aptamers against lactate dehydrogenase via SELEX and high-throughput sequencing
por: Guo, Linghui, et al.
Publicado: (2021)

Unveiling the Configurational Landscape of Carbamate: Paving the Way for Designing Functional Sequence-Defined Polymers
por: Perez Mellor, Ariel F., et al.
Publicado: (2023)

Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer
por: Grigsby, Christopher L., et al.
Publicado: (2013)

Editorial: In vitro mechanistic evaluation of nucleic acid polymers: A cautionary tale
por: Vaillant, Andrew
Publicado: (2022)

Stability Criterion for the Assembly of Core–Shell Lipid–Polymer–Nucleic Acid Nanoparticles
por: Paris, Juan L., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8mhu0vp0407o8kseql5vm86r47