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Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia

BACKGROUND: Undiagnosed diabetes mellitus cases are at higher risk for diabetic related complications. In low-income African countries, patients with undiagnosed diabetes mellitus account for 75% of diabetes cases. Psychiatric disorders have a greater impact on the global burden of diseases and disa...

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Autores principales: Asmelash, Daniel, Getnet, Wondale, Biadgo, Belete, Ambachew, Sintayehu, Melak, Tadele, Melese, Lemmesa, Damite, Shiwaneh, Baynes, Habtamu Wondifraw, Abebe, Molla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866284/
https://www.ncbi.nlm.nih.gov/pubmed/29622902
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author Asmelash, Daniel
Getnet, Wondale
Biadgo, Belete
Ambachew, Sintayehu
Melak, Tadele
Melese, Lemmesa
Damite, Shiwaneh
Baynes, Habtamu Wondifraw
Abebe, Molla
author_facet Asmelash, Daniel
Getnet, Wondale
Biadgo, Belete
Ambachew, Sintayehu
Melak, Tadele
Melese, Lemmesa
Damite, Shiwaneh
Baynes, Habtamu Wondifraw
Abebe, Molla
author_sort Asmelash, Daniel
collection PubMed
description BACKGROUND: Undiagnosed diabetes mellitus cases are at higher risk for diabetic related complications. In low-income African countries, patients with undiagnosed diabetes mellitus account for 75% of diabetes cases. Psychiatric disorders have a greater impact on the global burden of diseases and disability associated with chronic diseases like diabetes mellitus and cardiovascular diseases. METHODS: Institution based cross-sectional study was conducted at the University of Gondar Hospital from February to April 2016. A total of 205 psychiatric patients aged above 15 years that were taking antipsychotic were included by the simple random sampling method. Fasting blood glucose, triglycerides and cholesterol level were determined from venous blood samples to evaluate diabetes mellitus based on WHO criteria. RESULTS: Among 205 psychiatric patients taking antipsychotics, 15(7.3%) had undiagnosed diabetes mellitus. Duration of antipsychotic treatment and sex had a statistically significant association with the prevalence of undiagnosed diabetes mellitus. As the duration of antipsychotic drug treatment increased by one year, the risk of having a diabetes mellitus increase by 1.47 times (AOR: 1.47 CI: 1.021–2.125). CONCLUSION: The prevalence of undiagnosed diabetes mellitus among psychiatry patients taking antipsychotics was higher than the estimated diabetes national prevalence of Ethiopia. Screening of diabetes mellitus in particular, patients having a longer duration of antipsychotic treatment is mandatory to bring more undiagnosed cases for medical attention.
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spelling pubmed-58662842018-04-05 Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia Asmelash, Daniel Getnet, Wondale Biadgo, Belete Ambachew, Sintayehu Melak, Tadele Melese, Lemmesa Damite, Shiwaneh Baynes, Habtamu Wondifraw Abebe, Molla Ethiop J Health Sci Original Article BACKGROUND: Undiagnosed diabetes mellitus cases are at higher risk for diabetic related complications. In low-income African countries, patients with undiagnosed diabetes mellitus account for 75% of diabetes cases. Psychiatric disorders have a greater impact on the global burden of diseases and disability associated with chronic diseases like diabetes mellitus and cardiovascular diseases. METHODS: Institution based cross-sectional study was conducted at the University of Gondar Hospital from February to April 2016. A total of 205 psychiatric patients aged above 15 years that were taking antipsychotic were included by the simple random sampling method. Fasting blood glucose, triglycerides and cholesterol level were determined from venous blood samples to evaluate diabetes mellitus based on WHO criteria. RESULTS: Among 205 psychiatric patients taking antipsychotics, 15(7.3%) had undiagnosed diabetes mellitus. Duration of antipsychotic treatment and sex had a statistically significant association with the prevalence of undiagnosed diabetes mellitus. As the duration of antipsychotic drug treatment increased by one year, the risk of having a diabetes mellitus increase by 1.47 times (AOR: 1.47 CI: 1.021–2.125). CONCLUSION: The prevalence of undiagnosed diabetes mellitus among psychiatry patients taking antipsychotics was higher than the estimated diabetes national prevalence of Ethiopia. Screening of diabetes mellitus in particular, patients having a longer duration of antipsychotic treatment is mandatory to bring more undiagnosed cases for medical attention. Research and Publications Office of Jimma University 2018-01 /pmc/articles/PMC5866284/ /pubmed/29622902 Text en © 2018 Daniel Asmelash, et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Asmelash, Daniel
Getnet, Wondale
Biadgo, Belete
Ambachew, Sintayehu
Melak, Tadele
Melese, Lemmesa
Damite, Shiwaneh
Baynes, Habtamu Wondifraw
Abebe, Molla
Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title_full Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title_fullStr Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title_full_unstemmed Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title_short Undiagnosed Diabetes Mellitus and Associated Factors among Psychiatric Patients Receiving Antipsychotic Drugs at The University of Gondar Hospital, Northwest Ethiopia
title_sort undiagnosed diabetes mellitus and associated factors among psychiatric patients receiving antipsychotic drugs at the university of gondar hospital, northwest ethiopia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866284/
https://www.ncbi.nlm.nih.gov/pubmed/29622902
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