Cargando…
IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the mechanisms driving progression remain incompletely defined. We previously reported that the IPF lung harbors fibrogenic mesenchymal progenitor cells (MPCs), which serve as a cell of origin for IPF fibroblasts. Prolif...
Autores principales: | Yang, Libang, Herrera, Jeremy, Gilbertsen, Adam, Xia, Hong, Smith, Karen, Benyumov, Alexey, Bitterman, Peter B., Henke, Craig A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866425/ https://www.ncbi.nlm.nih.gov/pubmed/28860143 http://dx.doi.org/10.1152/ajplung.00200.2017 |
Ejemplares similares
-
Hypoxia enhances IPF mesenchymal progenitor cell fibrogenicity via the lactate/GPR81/HIF1α pathway
por: Yang, Libang, et al.
Publicado: (2023) -
A CD44/Brg1 nuclear complex confers mesenchymal progenitor cells with enhanced fibrogenicity in idiopathic pulmonary fibrosis
por: Yang, Libang, et al.
Publicado: (2021) -
Single-cell RNA sequencing reveals that lung mesenchymal progenitor cells in IPF exhibit pathological features early in their differentiation trajectory
por: Beisang, Daniel J., et al.
Publicado: (2020) -
Proteomic analysis of the IPF mesenchymal progenitor cell nuclear proteome identifies abnormalities in key nodal proteins that underlie their fibrogenic phenotype
por: Yang, Libang, et al.
Publicado: (2022) -
The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis
por: Stephenson, Katherine E., et al.
Publicado: (2023)