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SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions

Despite the many approaches to study differential splicing from RNA-seq, many challenges remain unsolved, including computing capacity and sequencing depth requirements. Here we present SUPPA2, a new method that addresses these challenges, and enables streamlined analysis across multiple conditions...

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Detalles Bibliográficos
Autores principales: Trincado, Juan L., Entizne, Juan C., Hysenaj, Gerald, Singh, Babita, Skalic, Miha, Elliott, David J., Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866513/
https://www.ncbi.nlm.nih.gov/pubmed/29571299
http://dx.doi.org/10.1186/s13059-018-1417-1