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SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions
Despite the many approaches to study differential splicing from RNA-seq, many challenges remain unsolved, including computing capacity and sequencing depth requirements. Here we present SUPPA2, a new method that addresses these challenges, and enables streamlined analysis across multiple conditions...
Autores principales: | Trincado, Juan L., Entizne, Juan C., Hysenaj, Gerald, Singh, Babita, Skalic, Miha, Elliott, David J., Eyras, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866513/ https://www.ncbi.nlm.nih.gov/pubmed/29571299 http://dx.doi.org/10.1186/s13059-018-1417-1 |
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