Central blockade of NLRP3 reduces blood pressure via regulating inflammation microenvironment and neurohormonal excitation in salt-induced prehypertensive rats

BACKGROUND: Inflammation has been implicated in the development of cardiovascular disease. We determined whether nod-like receptor with pyrin domain containing 3 (NLRP3) involved in the process of prehypertension, central blockade of NLRP3 decreased inflammation reaction, regulated neurohormonal exc...

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Detalles Bibliográficos
Autores principales: Wang, Mo-Lin, Kang, Yu-Ming, Li, Xiao-Guang, Su, Qing, Li, Hong-Bao, Liu, Kai-Li, Fu, Li-Yan, Saahene, Roland Osei, Li, Ying, Tan, Hong, Yu, Xiao-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866519/
https://www.ncbi.nlm.nih.gov/pubmed/29573749
http://dx.doi.org/10.1186/s12974-018-1131-7

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