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hMENA is a key regulator in endothelin-1/β-arrestin1–induced invadopodial function and metastatic process

Aberrant activation of endothelin-1 receptors (ET-1R) elicits pleiotropic effects relevant for tumor progression. The network activated by this receptor might be finely, spatially, and temporarily orchestrated by β-arrestin1 (β-arr1)–driven interactome. Here, we identify hMENA, a member of the actin...

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Detalles Bibliográficos
Autores principales: Di Modugno, Francesca, Caprara, Valentina, Chellini, Lidia, Tocci, Piera, Spadaro, Francesca, Ferrandina, Gabriella, Sacconi, Andrea, Blandino, Giovanni, Nisticò, Paola, Bagnato, Anna, Rosanò, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866561/
https://www.ncbi.nlm.nih.gov/pubmed/29439204
http://dx.doi.org/10.1073/pnas.1715998115