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hMENA is a key regulator in endothelin-1/β-arrestin1–induced invadopodial function and metastatic process
Aberrant activation of endothelin-1 receptors (ET-1R) elicits pleiotropic effects relevant for tumor progression. The network activated by this receptor might be finely, spatially, and temporarily orchestrated by β-arrestin1 (β-arr1)–driven interactome. Here, we identify hMENA, a member of the actin...
Autores principales: | Di Modugno, Francesca, Caprara, Valentina, Chellini, Lidia, Tocci, Piera, Spadaro, Francesca, Ferrandina, Gabriella, Sacconi, Andrea, Blandino, Giovanni, Nisticò, Paola, Bagnato, Anna, Rosanò, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866561/ https://www.ncbi.nlm.nih.gov/pubmed/29439204 http://dx.doi.org/10.1073/pnas.1715998115 |
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