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Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

Treatment of bacterial infections is becoming a serious clinical challenge due to the global dissemination of multidrug antibiotic resistance, necessitating the search for alternative treatments to disarm the virulence mechanisms underlying these infections. Uropathogenic Escherichia coli (UPEC) emp...

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Detalles Bibliográficos
Autores principales:	Kalas, Vasilios, Hibbing, Michael E., Maddirala, Amarendar Reddy, Chugani, Ryan, Pinkner, Jerome S., Mydock-McGrane, Laurel K., Conover, Matt S., Janetka, James W., Hultgren, Scott J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866590/ https://www.ncbi.nlm.nih.gov/pubmed/29507247 http://dx.doi.org/10.1073/pnas.1720140115

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