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hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons
Disturbed RNA processing and subcellular transport contribute to the pathomechanisms of motoneuron diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. RNA-binding proteins are involved in these processes, but the mechanisms by which they regulate the subcellular diversity of...
Autores principales: | Briese, Michael, Saal-Bauernschubert, Lena, Ji, Changhe, Moradi, Mehri, Ghanawi, Hanaa, Uhl, Michael, Appenzeller, Silke, Backofen, Rolf, Sendtner, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866599/ https://www.ncbi.nlm.nih.gov/pubmed/29507242 http://dx.doi.org/10.1073/pnas.1721670115 |
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