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High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA
The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (H(N)) and a receptor-binding domain (H(C)). Here w...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866713/ https://www.ncbi.nlm.nih.gov/pubmed/29576992 http://dx.doi.org/10.7717/peerj.4552 |