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Dexibuprofen nanocrystals with improved therapeutic performance: fabrication, characterization, in silico modeling, and in vivo evaluation

BACKGROUND: The aim of this study was to prepare and evaluate the impact of polymers on fabricating stable dexibuprofen (Dexi) nanocrystals with enhanced therapeutic potential, using a low energy, anti-solvent precipitation method coupled with molecular modelling approach. METHODS: Dexi nanocrystals...

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Detalles Bibliográficos
Autores principales:	Ullah, Naseem, Khan, Shahzeb, Ahmed, Shaimaa, Govender, Thirumala, Faidah, Hani S, de Matas, Marcel, Shahid, Muhammad, Minhas, Muhammad Usman, Sohail, Muhammad, Khurram, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866724/ https://www.ncbi.nlm.nih.gov/pubmed/29599613 http://dx.doi.org/10.2147/IJN.S151597

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