Interaction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells

BACKGROUND: Poly-l-lysine (PLL) enhances nanoparticle (NP) uptake, but the molecular mechanism remains unresolved. We asked whether PLL may interact with negatively charged glycoconjugates on the cell surface and facilitate uptake of magnetic NPs (MNPs) by tumor cells. METHODS: PLL-coated MNPs (PLL-...

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Detalles Bibliográficos
Autores principales: Siow, Wei Xiong, Chang, Yi-Ting, Babič, Michal, Lu, Yi-Ching, Horák, Daniel, Ma, Yunn-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866726/
https://www.ncbi.nlm.nih.gov/pubmed/29599614
http://dx.doi.org/10.2147/IJN.S156029

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