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In vitro biotransformation of pyrrolizidine alkaloids in different species. Part I: Microsomal degradation

Pyrrolizidine alkaloids (PA) are secondary metabolites of certain flowering plants. The ingestion of PAs may result in acute and chronic effects in man and livestock with hepatotoxicity, mutagenicity, and carcinogenicity being identified as predominant effects. Several hundred PAs sharing the diol p...

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Detalles Bibliográficos
Autores principales:	Kolrep, Franziska, Numata, Jorge, Kneuer, Carsten, Preiss-Weigert, Angelika, Lahrssen-Wiederholt, Monika, Schrenk, Dieter, These, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Toxicokinetics and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866832/ https://www.ncbi.nlm.nih.gov/pubmed/29143854 http://dx.doi.org/10.1007/s00204-017-2114-7

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