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The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis

The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practic...

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Autores principales: Gasparini, Giulio, Saponaro, Gianmarco, Gasparini, Daniela, Foresta, Enrico, Azzuni, Camillo, Adduci, Alessia, Boniello, Roberto, Moro, Alessandro, De Angelis, Paolo, Di Nardo, Francesco, Damato, Giuseppe, Doneddu, Piero, Todaro, Mattia, Garagiola, Umberto, Pelo, Sando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866890/
https://www.ncbi.nlm.nih.gov/pubmed/29713640
http://dx.doi.org/10.1155/2018/1868254
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author Gasparini, Giulio
Saponaro, Gianmarco
Gasparini, Daniela
Foresta, Enrico
Azzuni, Camillo
Adduci, Alessia
Boniello, Roberto
Moro, Alessandro
De Angelis, Paolo
Di Nardo, Francesco
Damato, Giuseppe
Doneddu, Piero
Todaro, Mattia
Garagiola, Umberto
Pelo, Sando
author_facet Gasparini, Giulio
Saponaro, Gianmarco
Gasparini, Daniela
Foresta, Enrico
Azzuni, Camillo
Adduci, Alessia
Boniello, Roberto
Moro, Alessandro
De Angelis, Paolo
Di Nardo, Francesco
Damato, Giuseppe
Doneddu, Piero
Todaro, Mattia
Garagiola, Umberto
Pelo, Sando
author_sort Gasparini, Giulio
collection PubMed
description The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients' part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.
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spelling pubmed-58668902018-04-30 The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis Gasparini, Giulio Saponaro, Gianmarco Gasparini, Daniela Foresta, Enrico Azzuni, Camillo Adduci, Alessia Boniello, Roberto Moro, Alessandro De Angelis, Paolo Di Nardo, Francesco Damato, Giuseppe Doneddu, Piero Todaro, Mattia Garagiola, Umberto Pelo, Sando Biomed Res Int Clinical Study The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients' part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives. Hindawi 2018-03-11 /pmc/articles/PMC5866890/ /pubmed/29713640 http://dx.doi.org/10.1155/2018/1868254 Text en Copyright © 2018 Giulio Gasparini et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Gasparini, Giulio
Saponaro, Gianmarco
Gasparini, Daniela
Foresta, Enrico
Azzuni, Camillo
Adduci, Alessia
Boniello, Roberto
Moro, Alessandro
De Angelis, Paolo
Di Nardo, Francesco
Damato, Giuseppe
Doneddu, Piero
Todaro, Mattia
Garagiola, Umberto
Pelo, Sando
The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title_full The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title_fullStr The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title_full_unstemmed The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title_short The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
title_sort use of ropivacaine in therapeutic treatment of oral aphthosis
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866890/
https://www.ncbi.nlm.nih.gov/pubmed/29713640
http://dx.doi.org/10.1155/2018/1868254
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