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Lactose repressor hinge domain independently binds DNA

The short 8–10 amino acid “hinge” sequence in lactose repressor (LacI), present in other LacI/GalR family members, links DNA and inducer‐binding domains. Structural studies of full‐length or truncated LacI‐operator DNA complexes demonstrate insertion of the dimeric helical “hinge” structure at the c...

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Detalles Bibliográficos
Autores principales:	Xu, Joseph S., Hewitt, Madeleine N., Gulati, Jaskeerat S., Cruz, Matthew A., Zhan, Hongli, Liu, Shirley, Matthews, Kathleen S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866929/ https://www.ncbi.nlm.nih.gov/pubmed/29318690 http://dx.doi.org/10.1002/pro.3372

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