Cargando…

Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes

Detalles Bibliográficos
Autor principal:	Cummings, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866992/ https://www.ncbi.nlm.nih.gov/pubmed/28767185 http://dx.doi.org/10.1111/cts.12491

Ejemplares similares

Clinical Trials for Disease-Modifying Therapies in Alzheimer’s Disease: A Primer, Lessons Learned, and a Blueprint for the Future(1)
por: Cummings, Jeffrey, et al.
Publicado: (2018)

Globalization of Alzheimer's disease clinical trials
por: Cummings, Jeffrey, et al.
Publicado: (2011)

Clinical trials in systemic sclerosis: lessons learned and outcomes
por: Matucci-Cerinic, Marco, et al.
Publicado: (2007)

Fluid Biomarkers in Clinical Trials of Alzheimer’s Disease Therapeutics
por: Ritter, Aaron, et al.
Publicado: (2015)

Neuroscience learning from longitudinal cohort studies of Alzheimer's disease: Lessons for disease-modifying drug programs and an introduction to the Center for Neurodegeneration and Translational Neuroscience
por: Ritter, Aaron, et al.
Publicado: (2018)

Biomarkers for Alzheimer’s Disease: Context of Use, Qualification, and Roadmap for Clinical Implementation
por: Cummings, Jeffrey, et al.
Publicado: (2022)

ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials
por: Wang, Jinping, et al.
Publicado: (2016)

Alzheimer's disease diagnostic criteria: practical applications
por: Cummings, Jeffrey
Publicado: (2012)

New approaches to symptomatic treatments for Alzheimer’s disease
por: Cummings, Jeffrey
Publicado: (2021)

A checklist for clinical trials in rare disease: obstacles and anticipatory actions—lessons learned from the FOR-DMD trial
por: Crow, Rebecca A., et al.
Publicado: (2018)

TREM2 Mediates Microglial Anti-Inflammatory Activations in Alzheimer’s Disease: Lessons Learned from Transcriptomics
por: Xue, Feng, et al.
Publicado: (2021)

Experimental Outcomes of the Mediterranean Diet: Lessons Learned from the Predimed Randomized Controlled Trial
por: Kargin, Dicle, et al.
Publicado: (2019)

Erythropoietin and organ protection: lessons from negative clinical trials
por: Pearl, Ronald G
Publicado: (2014)

The Rationale Behind the New Alzheimer’s Disease Conceptualization: Lessons Learned During the Last Decades
por: Molinuevo, José Luis, et al.
Publicado: (2018)

The overlap between vascular disease and Alzheimer’s disease - lessons from pathology
por: Attems, Johannes, et al.
Publicado: (2014)

Trial design innovations: Clinical trials for treatment of neuropsychiatric symptoms in Alzheimer's Disease
por: Cummings, J, et al.
Publicado: (2015)

Challenges and Lessons Learned From COVID-19 Trials: Should We Be Doing Clinical Trials Differently?
por: Janiaud, Perrine, et al.
Publicado: (2021)

The “rights” of precision drug development for Alzheimer’s disease
por: Cummings, Jeffrey, et al.
Publicado: (2019)

Learning the Lessons of the BSE Crisis
por: Cummings, Louise
Publicado: (2010)

Lessons from Multicenter Studies on CSF Biomarkers for Alzheimer's Disease
por: Mattsson, Niklas, et al.
Publicado: (2010)

Enrichment factors for clinical trials in mild-to-moderate Alzheimer's disease
por: Ballard, Clive, et al.
Publicado: (2019)

Patent Ductus Arteriosus Clinical Trials: Lessons Learned and Future Directions
por: Smith, Aisling, et al.
Publicado: (2021)

APOE targeting strategy in Alzheimer’s disease: lessons learned from protective variants
por: Bu, Guojun
Publicado: (2022)

Clinical Trial Endpoints and Their Clinical Meaningfulness in Early Stages of Alzheimer’s Disease
por: Cohen, S., et al.
Publicado: (2022)

Treatment Combinations for Alzheimer’s Disease: Current and Future Pharmacotherapy Options
por: Cummings, Jeffrey L., et al.
Publicado: (2019)

Inclusionary Trials: A Review of Lessons Not Learned
por: Adkins-Jackson, Paris B, et al.
Publicado: (2022)

Neuroinflammation in the Aging Down Syndrome Brain; Lessons from Alzheimer's Disease
por: Wilcock, Donna M.
Publicado: (2012)

Clinical holds for cell and gene therapy trials: Risks, impact, and lessons learned
por: Wills, Carolyn A., et al.
Publicado: (2023)

Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
por: Xie, Liming, et al.
Publicado: (2022)

Clinical Trials and Novel Pathogens: Lessons Learned from SARS
por: Muller, Matthew P., et al.
Publicado: (2004)

Highlighting the value of Alzheimer’s disease-focused registries: lessons learned from cancer surveillance
por: Miller, Margaret C., et al.
Publicado: (2023)

Mild Traumatic Brain Injury: Lessons Learned from Clinical, Sports, and Combat Concussions
por: Kelly, Judy C., et al.
Publicado: (2012)

Drug candidates in clinical trials for Alzheimer’s disease
por: Hung, Shih-Ya, et al.
Publicado: (2017)

Alzheimer's disease drug development pipeline: 2017
por: Cummings, Jeffrey, et al.
Publicado: (2017)

Imaging endpoints for clinical trials in Alzheimer’s disease
por: Cash, David M, et al.
Publicado: (2014)

Clinical trials of new drugs for Alzheimer disease
por: Huang, Li-Kai, et al.
Publicado: (2020)

Meaningful benefit and minimal clinically important difference (MCID) in Alzheimer's disease: Open peer commentary
por: Cummings, Jeffrey
Publicado: (2023)

Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification
por: Cummings, Jeffrey L., et al.
Publicado: (2023)

Lessons on Differential Neuronal-Death-Vulnerability from Familial Cases of Parkinson’s and Alzheimer’s Diseases
por: Franco, Rafael, et al.
Publicado: (2019)

Alzheimer's Disease and Vascular Deficiency: Lessons from Imaging Studies and Down Syndrome
por: Reed-Cossairt, Arlene, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8mip7nklecdtfs8vtssk3crns4