Clostridium difficile toxin B induces autophagic cell death in colonocytes

Toxin B (TcdB) is a major pathogenic factor of Clostridum difficile. However, the mechanism by which TcdB exerts its cytotoxic action in host cells is still not completely known. Herein, we report for the first time that TcdB induced autophagic cell death in cultured human colonocytes. The induction...

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Detalles Bibliográficos
Autores principales: Chan, Hung, Zhao, Shan, Zhang, Lin, Ho, Jeffery, Leung, Czarina C.H., Wong, Wai T., Tian, Yuanyuan, Liu, Xiaodong, Kwong, Thomas N.Y., Chan, Raphael C.Y., Yu, Sidney S.B., Wang, Maggie H.T., Tse, Gary, Wong, Sunny H., Chan, Matthew T.V., Wu, William K.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867081/
https://www.ncbi.nlm.nih.gov/pubmed/29383879
http://dx.doi.org/10.1111/jcmm.13555

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