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Titania‐Coated Gold Nano‐Bipyramids for Blocking Autophagy Flux and Sensitizing Cancer Cells to Proteasome Inhibitor‐Induced Death

Targeting protein degradation is recognized as a valid approach to cancer therapy. The ubiquitin–proteasome system (UPS) and the autophagy–lysosome pathway are two major pathways for intracellular protein degradation. Proteasome inhibitors such as bortezomib are clinically approved for treating mali...

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Detalles Bibliográficos
Autores principales: Wan, Hong‐Ye, Chen, Jian‐Li, Zhu, Xingzhong, Liu, Liang, Wang, Jianfang, Zhu, Xiao‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867123/
https://www.ncbi.nlm.nih.gov/pubmed/29593960
http://dx.doi.org/10.1002/advs.201700585