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Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK‐ERK signalling pathway in vivo and in vitro

Recent findings demonstrate that leptin plays a significant role in chondrocyte and osteoblast differentiation. However, the mechanisms by which leptin acts on cartilage endplate (CEP) cells to give rise to calcification are still unclear. The aim of this study was to evaluate the effects of leptin...

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Detalles Bibliográficos
Autores principales: Han, Ying‐Chao, Ma, Bin, Guo, Song, Yang, Mingjie, Li, Li‐Jun, Wang, Shan‐Jin, Tan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867127/
https://www.ncbi.nlm.nih.gov/pubmed/29372627
http://dx.doi.org/10.1111/jcmm.13398

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