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Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK‐ERK signalling pathway in vivo and in vitro
Recent findings demonstrate that leptin plays a significant role in chondrocyte and osteoblast differentiation. However, the mechanisms by which leptin acts on cartilage endplate (CEP) cells to give rise to calcification are still unclear. The aim of this study was to evaluate the effects of leptin...
Autores principales: | Han, Ying‐Chao, Ma, Bin, Guo, Song, Yang, Mingjie, Li, Li‐Jun, Wang, Shan‐Jin, Tan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867127/ https://www.ncbi.nlm.nih.gov/pubmed/29372627 http://dx.doi.org/10.1111/jcmm.13398 |
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