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A 1000 Arab genome project to study the Emirati population
Discoveries from the human genome, HapMap, and 1000 genome projects have collectively contributed toward the creation of a catalog of human genetic variations that has improved our understanding of human diversity. Despite the collegial nature of many of these genome study consortiums, which has led...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867278/ https://www.ncbi.nlm.nih.gov/pubmed/29410509 http://dx.doi.org/10.1038/s10038-017-0402-y |
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author | Al-Ali, Mariam Osman, Wael Tay, Guan K. AlSafar, Habiba S. |
author_facet | Al-Ali, Mariam Osman, Wael Tay, Guan K. AlSafar, Habiba S. |
author_sort | Al-Ali, Mariam |
collection | PubMed |
description | Discoveries from the human genome, HapMap, and 1000 genome projects have collectively contributed toward the creation of a catalog of human genetic variations that has improved our understanding of human diversity. Despite the collegial nature of many of these genome study consortiums, which has led to the cataloging of genetic variations of different ethnic groups from around the world, genome data on the Arab population remains overwhelmingly underrepresented. The National Arab Genome project in the United Arab Emirates (UAE) aims to address this deficiency by using Next Generation Sequencing (NGS) technology to provide data to improve our understanding of the Arab genome and catalog variants that are unique to the Arab population of the UAE. The project was conceived to shed light on the similarities and differences between the Arab genome and those of the other ethnic groups. |
format | Online Article Text |
id | pubmed-5867278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-58672782018-03-28 A 1000 Arab genome project to study the Emirati population Al-Ali, Mariam Osman, Wael Tay, Guan K. AlSafar, Habiba S. J Hum Genet Correspondence Discoveries from the human genome, HapMap, and 1000 genome projects have collectively contributed toward the creation of a catalog of human genetic variations that has improved our understanding of human diversity. Despite the collegial nature of many of these genome study consortiums, which has led to the cataloging of genetic variations of different ethnic groups from around the world, genome data on the Arab population remains overwhelmingly underrepresented. The National Arab Genome project in the United Arab Emirates (UAE) aims to address this deficiency by using Next Generation Sequencing (NGS) technology to provide data to improve our understanding of the Arab genome and catalog variants that are unique to the Arab population of the UAE. The project was conceived to shed light on the similarities and differences between the Arab genome and those of the other ethnic groups. Nature Publishing Group UK 2018-02-06 2018 /pmc/articles/PMC5867278/ /pubmed/29410509 http://dx.doi.org/10.1038/s10038-017-0402-y Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, and provide a link to the Creative Commons license. You do not have permission under this license to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Correspondence Al-Ali, Mariam Osman, Wael Tay, Guan K. AlSafar, Habiba S. A 1000 Arab genome project to study the Emirati population |
title | A 1000 Arab genome project to study the Emirati population |
title_full | A 1000 Arab genome project to study the Emirati population |
title_fullStr | A 1000 Arab genome project to study the Emirati population |
title_full_unstemmed | A 1000 Arab genome project to study the Emirati population |
title_short | A 1000 Arab genome project to study the Emirati population |
title_sort | 1000 arab genome project to study the emirati population |
topic | Correspondence |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867278/ https://www.ncbi.nlm.nih.gov/pubmed/29410509 http://dx.doi.org/10.1038/s10038-017-0402-y |
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