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Novel Concepts of Altered Immunoglobulin G Galactosylation in Autoimmune Diseases

The composition of the conserved N297 glycan in immunoglobulin G (IgG) has been shown to affect antibody effector functions via C1q of the complement system and Fc gamma receptors (FcγR) on immune cells. Changes in the general levels of IgG-glycoforms, such as lowered total IgG galactosylation obser...

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Detalles Bibliográficos
Autores principales:	Dekkers, Gillian, Rispens, Theo, Vidarsson, Gestur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867308/ https://www.ncbi.nlm.nih.gov/pubmed/29616041 http://dx.doi.org/10.3389/fimmu.2018.00553

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