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Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study
OBJECTIVES: There is a need for effective and safe treatment during pregnancy in women with chronic inflammatory diseases. This study evaluated placental transfer of certolizumab pegol (CZP), an Fc-free anti-tumour necrosis factor drug, from CZP-treated pregnant women to their infants. METHODS: CRIB...
Autores principales: | Mariette, Xavier, Förger, Frauke, Abraham, Bincy, Flynn, Ann D, Moltó, Anna, Flipo, René-Marc, van Tubergen, Astrid, Shaughnessy, Laura, Simpson, Jeff, Teil, Marie, Helmer, Eric, Wang, Maggie, Chakravarty, Eliza F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867410/ https://www.ncbi.nlm.nih.gov/pubmed/29030361 http://dx.doi.org/10.1136/annrheumdis-2017-212196 |
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