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Tauroursodeoxycholic Acid Protects Nucleus Pulposus Cells from Compression-Induced Apoptosis and Necroptosis via Inhibiting Endoplasmic Reticulum Stress
Tauroursodeoxycholic acid (TUDCA) is a kind of hydrophilic bile acid, which could protect cells from death via inhibiting endoplasmic reticulum (ER) stress. However, the role of TUDCA in compression-induced intervertebral disc degeneration (IVDD) has not been elucidated. Here, we used a previously d...
Autores principales: | Wang, Wenzheng, Qing, Xiangcheng, Wang, Baichuan, Ma, Kaige, Wei, Yulong, Shao, Zengwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867595/ https://www.ncbi.nlm.nih.gov/pubmed/29721028 http://dx.doi.org/10.1155/2018/6719460 |
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