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ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A

Our understanding of autophagy and lysosomal function has been greatly enhanced by the discovery of natural product structures that can serve as chemical probes to reveal new patterns of signal transduction in cells. Coibamide A is a cytotoxic marine natural product that induces mTOR-independent aut...

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Detalles Bibliográficos
Autores principales:	Wan, Xuemei, Serrill, Jeffrey D., Humphreys, Ian R., Tan, Michelle, McPhail, Kerry L., Ganley, Ian G., Ishmael, Jane E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867621/ https://www.ncbi.nlm.nih.gov/pubmed/29494533 http://dx.doi.org/10.3390/md16030077

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