The effects of PI3K-mediated signalling on glioblastoma cell behaviour

The PI3K/Akt/mTOR signalling network is activated in almost 90% of all glioblastoma, the most common primary brain tumour, which is almost invariably lethal within 15 months of diagnosis. Despite intensive research, modulation of this signalling cascade has so far yielded little therapeutic benefit,...

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Detalles Bibliográficos
Autores principales: Langhans, Julia, Schneele, Lukas, Trenkler, Nancy, von Bandemer, Hélène, Nonnenmacher, Lisa, Karpel-Massler, Georg, Siegelin, Markus D., Zhou, Shaoxia, Halatsch, Marc-Eric, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868055/
https://www.ncbi.nlm.nih.gov/pubmed/29184057
http://dx.doi.org/10.1038/s41389-017-0004-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868055/
https://www.ncbi.nlm.nih.gov/pubmed/29184057
http://dx.doi.org/10.1038/s41389-017-0004-8

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