Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare

Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery. The work uses very sensitive prion assays now available for medical research, and may...

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Detalles Bibliográficos
Autores principales: Nihat, Akin, Mead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868066/
https://www.ncbi.nlm.nih.gov/pubmed/29580258
http://dx.doi.org/10.1186/s13073-018-0536-3
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author Nihat, Akin
Mead, Simon
author_facet Nihat, Akin
Mead, Simon
author_sort Nihat, Akin
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description Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery. The work uses very sensitive prion assays now available for medical research, and may soon be adapted to related neurodegenerative disorders.
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spelling pubmed-58680662018-03-29 Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare Nihat, Akin Mead, Simon Genome Med Comment Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery. The work uses very sensitive prion assays now available for medical research, and may soon be adapted to related neurodegenerative disorders. BioMed Central 2018-03-26 /pmc/articles/PMC5868066/ /pubmed/29580258 http://dx.doi.org/10.1186/s13073-018-0536-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Nihat, Akin
Mead, Simon
Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title_full Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title_fullStr Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title_full_unstemmed Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title_short Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
title_sort detection of creutzfeldt-jakob disease prions in skin: implications for healthcare
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868066/
https://www.ncbi.nlm.nih.gov/pubmed/29580258
http://dx.doi.org/10.1186/s13073-018-0536-3
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