The emerging roles of exosomes in the modulation of immune responses in cancer

Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss h...

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Detalles Bibliográficos
Autores principales: Kurywchak, Paul, Tavormina, Jena, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868069/
https://www.ncbi.nlm.nih.gov/pubmed/29580275
http://dx.doi.org/10.1186/s13073-018-0535-4
Descripción
Sumario:Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss how exosomes could be exploited as biomarkers and delivery vehicles in cancer therapy.

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